Further information
Fipronil is a member of the phenylpyrazole family of non-systemic insecticides/acaricides, which acts by blocking the GABA receptor to kill the target parasite on contact.
FRONTLINE Spot On Cat is effective against fleas for up to 5 weeks in cats and prevents re-infestation with all stages of Rhipicephalus spp., Dermacentor spp., and Ixodes spp. ticks for up to one month, depending on the level of environmental challenge. Newly arriving fleas are killed within 24 hours of landing on the animal. Re-treatment may safely be carried out at one month intervals.
FRONTLINE Spot On Cat is licensed for use as part of a strategy for the treatment of Flea Allergy Dermatitis. For this condition, monthly application to the allergic patient and to other cats in the household is recommended.
FRONTLINE Spot On Cat does not prevent ticks attaching to the animal, but ticks will be killed in the first 24-48 hours after attachment. Once dead, ticks will often drop off the animal, but any remaining ticks may easily be removed by a gently pull, preferably using tweezers. There may be an attachment of single ticks. For this reason transmission of infectious diseases cannot be completed excluded if conditions are unfavourable.
For optimum control of flea problems in a multi-pet household, all dogs and cats in the household should be treated with a suitable insecticide. Fleas from pets often infest the animal's basket, bedding and regular resting areas such as carpets and soft furnishings which should be treated, in case of massive infestation and at the beginning of the control measures, with a suitable insecticide and vacuumed regularly.
When treating infestations of lice, all in-contact cats should be treated with an appropriate product at the same time.
Laboratory studies using fipronil have not shown any teratogenic or embryotoxic effect.
The safety of the product was demonstrated in breeding, pregnant and lactating queens treated with multiple consecutive doses with up to 3 times the maximum recommended dose. FRONTLINE Spot On Cat can be used in breeding, pregnant and lactating queens.
No adverse effects have been seen in cats and kittens aged 8 weeks or older and weighing about 1kg treated monthly with five times the recommended dose for six consecutive months. However, the risk of adverse effects may increase with overdosing. Itching may occur following treatment.
After the topical application of FRONTLINE Spot On Cat, the products will spread from the site of treatment to cover the entire surface of the animal within 24 hours. After application, absorption of fipronil through the skin is negligible.
No known incompatibilities exist for the use of other insecticides or flea control products concurrently with FRONTLINE Spot On Cat.
There are no data available on the effect of bathing and shampooing on the efficacy of FRONTLINE Spot On Cat in cats. However, based on information available for dogs shampooed from 2 days after application of the product, it is not recommend to bath animals within 2 days after application of FRONTLINE Spot On Cat.
The alcohol carrier may have adverse effects on painted, varnished or other household surfaces or furnishings.